Each mL contains:
● Moxifloxacin Hydrochloride IP equivalent to Moxifloxacin – 5.0 mg
● Loteprednol Etabonate – 5.0 mg
● Sterile Aqueous Base – q.s.
Ophthalmic Suspension
MOXIRES-LP is a dual-action ophthalmic formulation that combines:
● Loteprednol Etabonate, a corticosteroid that controls inflammation by inhibiting inflammatory mediators.
● Moxifloxacin, a broad-spectrum fourth-generation fluoroquinolone effective against bacterial infections.
This combination is ideal for treating ocular conditions involving both inflammation and infection.
Loteprednol Etabonate:
● Inhibits the inflammatory response to a wide range of inciting agents.
● Suppresses edema, capillary dilation, leukocyte migration, and collagen formation.
● Reduces scar formation, fibrin deposition, and other signs of inflammation.
● Acts by blocking phospholipase A2, preventing synthesis of pro-inflammatory mediators like prostaglandins and leukotrienes.
● An 8-methoxy fluoroquinolone that blocks bacterial DNA replication.
● Inhibits DNA gyrase and topoisomerase IV, enzymes essential for bacterial growth.
● Effective against gram-positive and gram-negative organisms.
● No observed cross-resistance with aminoglycosides, tetracyclines, or β-lactam antibiotics.
MOXIRES-LP is indicated for the treatment of:
● Bacterial conjunctivitis caused by susceptible strains of aerobic gram-positive and aerobic gram-negative microorganisms
● Ocular conditions with steroid-responsive inflammation
● Store in a cool and dark place
● Protect from light
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